Saffron for Depression: Evidence From 12 Clinical Trials

Saffron spice threads next to supplement capsule illustrating saffron's antidepressant research

Saffron extract at 30mg/day has shown antidepressant effects equivalent to fluoxetine in controlled trials. Here is what the clinical evidence actually shows, the mechanism, the correct dose, and the quality issues that make most commercial products unreliable.